Big Data in Omics and Imaging: Integrated Analysis and Causal Inference addresses the recent development of integrated genomic, epigenomic and imaging data analysis and causal inference in big data era. Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), genome-wide expression studies (GWES), and epigenome-wide association studies (EWAS), the overall contribution of the new identified genetic variants is small and a large fraction of genetic ...
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Big Data in Omics and Imaging: Integrated Analysis and Causal Inference addresses the recent development of integrated genomic, epigenomic and imaging data analysis and causal inference in big data era. Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), genome-wide expression studies (GWES), and epigenome-wide association studies (EWAS), the overall contribution of the new identified genetic variants is small and a large fraction of genetic variants is still hidden. Understanding the etiology and causal chain of mechanism underlying complex diseases remains elusive. It is time to bring big data, machine learning and causal revolution to developing a new generation of genetic analysis for shifting the current paradigm of genetic analysis from shallow association analysis to deep causal inference and from genetic analysis alone to integrated omics and imaging data analysis for unraveling the mechanism of complex diseases. FEATURES Provides a natural extension and companion volume to Big Data in Omic and Imaging: Association Analysis, but can be read independently. Introduce causal inference theory to genomic, epigenomic and imaging data analysis Develop novel statistics for genome-wide causation studies and epigenome-wide causation studies. Bridge the gap between the traditional association analysis and modern causation analysis Use combinatorial optimization methods and various causal models as a general framework for inferring multilevel omic and image causal networks Present statistical methods and computational algorithms for searching causal paths from genetic variant to disease Develop causal machine learning methods integrating causal inference and machine learning Develop statistics for testing significant difference in directed edge, path, and graphs, and for assessing causal relationships between two networks The book is designed for graduate students and researchers in genomics, epigenomics, medical image, bioinformatics, and data science. Topics covered are: mathematical formulation of causal inference, information geometry for causal inference, topology group and Haar measure, additive noise models, distance correlation, multivariate causal inference and causal networks, dynamic causal networks, multivariate and functional structural equation models, mixed structural equation models, causal inference with confounders, integer programming, deep learning and differential equations for wearable computing, genetic analysis of function-valued traits, RNA-seq data analysis, causal networks for genetic methylation analysis, gene expression and methylation deconvolution, cell -specific causal networks, deep learning for image segmentation and image analysis, imaging and genomic data analysis, integrated multilevel causal genomic, epigenomic and imaging data analysis.
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Add this copy of Discourse on the Worship of Priapus and Its Connection to cart. $22.18, very good condition, Sold by Book Alley rated 4.0 out of 5 stars, ships from Pasadena, CA, UNITED STATES, published 1942 by Kessinger Publishing, LLC.
Add this copy of A Discourse on the Worship of Priapus and Its to cart. $37.00, good condition, Sold by Books From California rated 4.0 out of 5 stars, ships from Simi Valley, CA, UNITED STATES, published 1925 by The Dilettanti Society.
Add this copy of A Discourse on the Worship of Priapus and Its to cart. $44.20, new condition, Sold by Books2anywhere rated 5.0 out of 5 stars, ships from Fairford, GLOUCESTERSHIRE, UNITED KINGDOM, published 2014 by Literary Licensing, LLC.
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PLEASE NOTE, WE DO NOT SHIP TO DENMARK. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK.
Add this copy of Discourse on the Worship of Priapus, and Its Connection to cart. $54.00, fair condition, Sold by Redux Books rated 5.0 out of 5 stars, ships from Wyoming, MI, UNITED STATES, published 1865 by London Privately Printed.
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Fair. Poor hardcover, 1894 printing. #448/500. Reading copy. Binding is not intact. All pages are present and unmarked, though lightly tanned. Backstrip is missing, covers are not attached to text block. Photos available upon request.; 100% Satisfaction Guaranteed! Ships same or next business day!
Add this copy of A Discourse on the Worship of Priapus: and Its to cart. $72.00, good condition, Sold by Taos Books rated 5.0 out of 5 stars, ships from Santa Fe, NM, UNITED STATES, published 1930 by The Dilettanti Society.
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Collectible: Good. Size: 8vo-over 7; This is just one volume of the two-volume set, but no indicator of which volume it is. Good condition, no dust jacket, undated limited edition, no. 369 of 625 printed, text tight clean and unmarked, age toning if present light and uniform, damp-stain on front board at tip and along fore-edge, damp-stain on back board along top edge, text unaffected.
Add this copy of A Discourse on the Worship of Priapus, and Its to cart. $258.00, very good condition, Sold by Powell's Books Chicago rated 5.0 out of 5 stars, ships from Chicago, IL, UNITED STATES.
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Very Good. 1894. Hardcover. Cloth, no dj. Privately printed in London, 1894 reprinting (first published 1865). Number 371 of 500 numbered copies. Stout 8vo. Blue cloth boards with gilt-stamped leather band on spine. xvi, 254 pp., 37 b&w plates. Minor rubbing and edge wear to boards; leather band on spine is somewhat scuffed. Expected age-toning to text block; approx. 2-inch tear at bottom edge of plate no. 37, not affecting illustration. Else very sound. A handsome volume. Very Good. (Subject: Ancient & Classical Studies).
Add this copy of A Discourse on the Worship of Priapus, and Its to cart. $330.08, very good condition, Sold by Bookcase rated 4.0 out of 5 stars, ships from Carlisle, UNITED KINGDOM, published 1952 by Charles Skilton.
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Very Good. 8vo. Limited ed no. 395 of 675 numbered copies. Attractively bound in half blue leather with blue cloth boards and grey marbled endpapers. TEG. Reprint of 1865 edition. Closed edges tanned, otherwise content clean and solid.
