The human race has enormous he terogenei ty, founded on genetic and environmental sources. Variability, therefore, is a vital dimension in any consideration of human risk assessment. In the estimation of risks, current methods of extrapolation based upon converting the response of a median man are inadequate, as they ignore phenotypic variation and there- fore, susceptible subgroups. There is a growing literature defining the extent of human variation in normal populations; thus, the normal young adult population may have ...
Read More
The human race has enormous he terogenei ty, founded on genetic and environmental sources. Variability, therefore, is a vital dimension in any consideration of human risk assessment. In the estimation of risks, current methods of extrapolation based upon converting the response of a median man are inadequate, as they ignore phenotypic variation and there- fore, susceptible subgroups. There is a growing literature defining the extent of human variation in normal populations; thus, the normal young adult population may have 10-20% known hyperreactors. How far can we ignore human variability in risk assessment? Should we be concerned with susceptible groups, and how can we modify the risk assessment analysis accordingly? The aim of our meeting was to bring together experts from the fields of human epidemiology, toxicology, aging, genetics, carcino- genesis and teratology, and to provide a forum in which we might assimi- late knowledge of human heterogeneity as a coherent whole. Since the resolution and obligations of risk assessment, in the last analysis, are a political process, we also involved representatives from the legal field, the unions, and the regulatory agencies. We are most grateful for financial support from the National Institute on Aging; the u. S. Environmental Protection Agency; the U. S. Department of Energy; FDA - National Center for Toxicological Research; The Council for Tobacco Research-USA, Inc; Johnson and Johnson; Merck Sharp and Dohme Research Laboratories; and Associated Universities, Inc. We thank our Symposium Coordinator, Ms.
Read Less
Add this copy of Phenotypic Variation in Populations: Relevance to Risk to cart. $112.32, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2013 by Springer.
Add this copy of Phenotypic Variation in Populations: Relevance to Risk to cart. $122.45, new condition, Sold by Ria Christie Books rated 4.0 out of 5 stars, ships from Uxbridge, MIDDLESEX, UNITED KINGDOM, published 2013 by Springer.
Add this copy of Phenotypic Variation in Populations: Relevance to Risk to cart. $12.00, like new condition, Sold by Basement Seller 101 rated 5.0 out of 5 stars, ships from Cincinnati, OH, UNITED STATES, published 1988 by Springer.
Add this copy of Phenotypic Variation in Populations: Relevance to Risk to cart. $22.50, new condition, Sold by Scholars Attic rated 4.0 out of 5 stars, ships from Lake Barrington, IL, UNITED STATES, published 1988 by PLENUM.
Add this copy of Phenotypic Variation in Populations: Relevance to Risk to cart. $41.29, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Santa Clarita, CA, UNITED STATES, published 1988 by Plenum Publishing Corporation.
Add this copy of Phenotypic Variation in Populations: Relevance to Risk to cart. $42.76, poor condition, Sold by Anybook rated 4.0 out of 5 stars, ships from Lincoln, UNITED KINGDOM, published 1988 by Plenum Press.
Choose your shipping method in Checkout. Costs may vary based on destination.
Seller's Description:
Volume 43. This is an ex-library book and may have the usual library/used-book markings inside. This book has hardback covers. In poor condition, suitable as a reading copy. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item, 850grams, ISBN: 030642794X.
